Mike Napoli hit one of five Cleveland home runs — a 462-foot blast that nearly hit the scoreboard in left field — and the host Indians routed the New York Yankees, 10-2, on Friday night.

Napoli’s two-run homer in the third inning landed near the top of the bleachers, a few feet below the scoreboard, for his 18th of the season.

Cleveland’s five home runs marked a season high, with three coming in the first inning. Jason Kipnis homered twice and Carlos Santana and Lonnie Chisenhall also hit home runs.

All-Star Corey Kluber (9-8) allowed one run — Brian McCann’s solo homer — in eight innings. Kluber gave up five hits, struck out eight and didn’t walk a batter.

Rookie Chad Green (1-2) allowed all four homers and was charged with seven runs in 4? innings.

Mark McGwire, playing for Oakland, is the only player to hit the scoreboard in the ballpark’s 22-year history on April 30, 1997. Jim Thome hit the longest home run, traveling 511 feet, on July 3, 1999.

The AL-Central leading Indians bounced back from Thursday’s 5-4 loss that ended when a replay review overturned a call that would have loaded the bases with two outs.

McCann homered in the sixth and had both RBIs for the Yankees, who are 3-5 on a 10-game trip going into the All-Star break.

Cleveland left no doubt about Friday’s game.

Santana and Kipnis started the first with home runs, coming on Green’s first eight pitches. Chisenhall added a two-run homer.

Napoli’s fifth-inning single gave him three RBIs while Kipnis homered again in the seventh.

Carlos Beltran, still nursing a sore hamstring, was 1 for 4 as the designated hitter and Alex Rodriguez didn’t play for the third straight game.

Marlins 3, Reds 1 — Jose Fernandez allowed one unearned run in seven innings to help host Miami defeat Cincinnati to begin the final series before the All-Star break.

Christian Yelich homered and drove in two runs and Derek Dietrich also knocked in a run for the Marlins, who returned home after a 3-6 road trip. Fernandez (11-4) struck out eight and did not walk a batter. He allowed six hits.

Reds second baseman Brandon Phillips was hit by Fernandez on the left hand in the seventh inning and X-rays revealed a hairline fracture.

Angels 9, Orioles 5 — Daniel Nava had two RBIs and made a spectacular catch to help Los Angeles beat host Baltimore for its fourth straight victory. Mike Trout scored three runs for the Angels, who built an 8-1 lead in the fourth inning against the AL East leaders.

Nationals 3, Mets 1 — Stephen Strasburg stayed undefeated, winning a marquee pitching matchup with an ailing Noah Syndergaard by tossing seven innings of two-hit ball that led visiting Washington over a banged-up New York squad. Mets star Yoenis Cespedes was pulled after three innings with a strained right quad and Syndergaard left in the fifth because of a bone spur in his right elbow.

Pirates 8, Cubs 4 — Andrew McCutchen had three hits, including an RBI single during a decisive four-run seventh inning, as host Pittsburgh rallied for a rare victory over Chicago and Jake Arrieta. John Jaso’s RBI single tied the score at 4-4 and chased Arrieta, who had beaten the Pirates in all three previous starts this season.

Rangers 6, Twins 5 — Rougned Odor and Elvis Andrus had RBI triples and Texas overcame a struggling start by All-Star lefthander Cole Hamels to defeat visiting Minnesota. Texas twice blew two-run leads before finally going ahead for good in the sixth. Nomar Mazara had a leadoff double against reliever Ryan Pressly (2-5) before Andrus tripled and scored the go-ahead run on Bobby Wilson’s sacrifice fly.

Blue Jays 6, Tigers 0 — J.A. Happ and two relievers combined on a seven-hit shutout, Edwin Encarnacion hit a three-run home run as host Toronto extended its season-high winning streak to seven games. The lefthanded Happ (12-3) matched his career-high in wins by giving up six hits, striking out nine and walking none.

Astros 10, Athletics 9 — Luis Valbuena drove in four runs, highlighted by a three-run homer with one out in the ninth to lift host Houston to a wild victory over Oakland. The Athletics took the lead with a five-run ninth before Jose Altuve singled with one out in the bottom of the inning. Carlos Correa struck out, but reached on a wild pitch before Valbuena connected off Ryan Madson (3-3).

Mariners 3, Royals 2 — Hisashi Iwakuma pitched into the seventh inning, allowing one run on five hits and three walks, Seattle scored the go-ahead runs on Yordano Ventura’s wild pitch and the Mariners held on to beat host Kansas City.

Brewers 4, Cardinals 3 — Jonathan Villar’s single drove in Kurt Nieuwenhuis from second base with two outs in the ninth inning as host Milwaukee got past St. Louis. The home plate umpire ruled Nieuwenhuis safe, which was confirmed after a brief review.

Braves 11, White Sox 8 —Freddie Freeman, Tyler Flowers and Nick Markakis all homered off Chris Sale to lead Atlanta over host Chicago. The White Sox turned their third triple play this season in the third — the only inning Atlanta didn’t score against Sale in his five innings.

Phillies 5, Rockies 3 — Tommy Joseph hit a pinch-hit, three-run home run in the seventh inning to help Philadelphia beat host Colorado.