Brad Whitford has a busy year ahead of him. The Aerosmith guitarist is currently on tour with his other band, Whitford/St. Holmes, and they’ll be coming to Boston to play at the House of Blues on June 25 to promote their new album, “Reunion.’’

Whitford/St. Holmes is a collaboration between Whitford and Derek St. Holmes. Both men live in Nashville and know what it’s like playing a supporting role in a big-time band (St. Holmes played in Ted Nugent’s).

Whitford and St. Holmes have a long history together that goes back to the late 1970s, when Aerosmith and Nugent shared a manager. The two guitarists began hanging out together and jamming (as guitarists tend to do) and put out their first Whitford/St. Holmes album in 1981. The duo maintained their friendship over the years, and began collaborating again after Whitford moved to Nashville about five years ago.

“We ended up basically being neighbors, said Whitford. “Living in proximity, we were just hanging out, playing and jamming, and it turned into lots of writing, and the result is this album and all that’s going to follow,’’ said Whitford.

Whitford and St. Holmes produced “Reunion’’ at The Castle Studios in Franklin, Tenn.

“I truly enjoy being in Nashville,’’ said Whitford. “You’re surrounded, knee-deep in a culture of music that’s unlike anywhere I’ve ever been. It’s a unique place, and I just love being there.’’

Whitford, who graduated from Reading Memorial High School in 1970, says he misses his friends from the Boston area, and he also misses the oysters, lobsters, and other seafood that’s so plentiful here.

Whitford said he’s looking forward to playing in Boston when Whitford/St. Holmes opens for Whitesnake at the House of Blues June 25. After the band’s tour wraps up, he’ll hit the road with Aerosmith. He said Aerosmith is slated to play South America in October and planning is underway for more tour dates through 2017.

“As long as I can play my guitar, I’m a happy camper,’’ said Whitford.