Starlin Castro and Austin Romine each had two RBIs, Alex Rodriguez had three hits, and the New York Yankees squandered most of a seven-run lead before escaping with an 8-6 victory over the Orioles on Saturday night in Baltimore.

New York led, 7-0, before the Orioles hit three homers in a six-run seventh. The Yankees then received a strong showing from the back end of their bullpen to make the advantage stand up.

Andrew Miller entered in the seventh and worked two perfect innings. After Rodriguez hit an RBI single in the ninth, Aroldis Chapman got three outs for his ninth save in nine tries.

New York finished with 16 hits, one short of its season high. It was the first time in 14 games that the Yankees scored more than six runs — a rare offensive outburst from a team that came in ranked last in the AL in batting average and 14th in runs.

Ivan Nova (4-3) took a three-hit shutout into the seventh but didn’t get another out.

Mark Trumbo led off with his 18th homer, Matt Wieters singled, and Pedro Alvarez hit a shot into the left-field seats. A single, a walk, and wild pitch ended Nova’s outing.

Nick Goody came in and lasted two pitches, the second of which Adam Jones launched over the left field wall to get the Orioles to 7-6.

Baltimore would not get another runner to first base until Jones drew a two-out walk in the ninth. Chapman then struck out pinch hitter Nolan Reimold to end it.

New York was without first baseman Mark Teixeira, who was placed on the 15-day disabled list before the game with a right knee articular cartilage tear.

Indians 7, Royals 1 — Francisco Lindor hit two doubles and one of Cleveland’s three home runs, leading the host Indians into first place in the AL Central.

The Indians will go for a sweep of the four-game series Sunday, and have won five of six against the Royals this season.

Lindor, whose two-run homer came in the seventh inning, became the first Indians player to record three extra-base hits in a game this season.

He also started an outstanding defensive play in the ninth. Playing in a shift near second base, he made a backhand stop of Kendrys Morales’s hard-hit grounder and flipped to third baseman Jose Ramirez, who was playing behind second. Ramirez threw to first for the out.

Tyler Naquin, who hit his first big league home run Friday, hit a two-run homer in the sixth. Mike Napoli started the four-run inning with a solo homer.

Josh Tomlin (8-1) bounced back from his first loss of the season and allowed one run in 6? innings.

Cubs 5, Diamondbacks 3 — Jason Hammel allowed one hit over seven innings and snapped a tie with a two-run single to lead the sizzling Cubs at Wrigley Field.

Dexter Fowler added his 17th career leadoff home run, Anthony Rizzo hit his 13th homer, and Hector Rondon pitched a perfect ninth to earn his 10th save for the Cubs, who have won four straight and 10 of 11.

Arizona went up, 2-0, on Jake Lamb’s 10th homer in the first following a walk. But Hammel (7-1) settled down and allowed only one more walk, retiring his last 13 batters

The Diamondbacks walked David Ross intentionally to load the bases in the fourth. Hammel responded with a grounder up the middle that got by Edwin Escobar (0-2), hit second base, and darted into right field to cap a three-run inning.

Chicago (39-15) has the best record in the majors and all five starters have sub-3.00 ERAs. The Cubs are 8-1 on a homestand that ends Sunday and are 5-1 against Arizona (24-34) which fell a season-worst 10 games under .500.

Reds 6, Nationals 3 — Stephen Strasburg gave up Joey Votto’s two-run homer and limped off the field a few pitches later, and host Cincinnati overcame a pair of rain delays and rallied past Washington for its fourth straight win.

Following a 64-minute rain delay in the bottom of the eighth, Adam Duvall hit Shawn Kelley’s fourth pitch for a tiebreaking three-run homer.

The Nationals had won Strasburg’s last 15 starts, which was the longest active streak in the major leagues.

Strasburg was holding a 2-1 lead when a cloudburst caused a 21-minute delay to the start of the sixth inning. Strasburg walked Zack Cozart to start the bottom of the inning, gave up Votto’s homer, and grabbed his right calf on a pitch to Brandon Phillips. He left a few pitches later, limping slightly.

Jay Bruce also homered off Strasburg, who fanned 10 and became the first Nationals pitcher to strike out 1,000 in his career.

Cardinals 7, Giants 4 — Rookie Aledmys Diaz lined a tying, three-run shot off the foul pole in the fifth inning, one of four homers in a span of nine at-bats against Jeff Samardzija, as host St. Louis beat San Francisco.

Brandon Moss got the long-ball binge started with his 11th leading off the fifth. Stephen Piscotty and Matt Adams hit consecutive homers in a matter of three pitches to open the sixth for a 6-4 cushion.

The rally rescued Michael Wacha, who left trailing 4-0 after five seemingly on track for a seventh consecutive loss. Wacha has allowed 23 earned runs in his last 23 innings.

Samardzija (7-4) had given up five homers in 80 innings all season, and just one in his previous five outings. He opened with four routine innings, permitting three singles and no runner past first base.

Tigers 7, White Sox 4 — J.D. Martinez homered and drove in three runs and Mike Pelfrey ended an 18-start winless string as host Detroit prevailed over Chris Sale.

Sale (9-2) failed again to become the first 10-game winner in the majors. He allowed four runs on nine hits in 6? innings, and is 0-2 in his last three starts.

Martinez hit a go-ahead home run in the sixth that helped Pelfrey post his first win since Aug.?12. He allowed two runs on five hits and three walks in six innings, striking out three.

After Mark Lowe allowed two runs in the ninth, Francisco Rodriguez got the final out for his 14th save.

Victor Martinez went 2 for 2 with a walk against Sale, and is now hitting .500 (18 for 36) against the Chicago ace in his career.

White Sox left fielder Jason Coats, making his major league debut, exited in the seventh inning after colliding with center fielder J.B. Shuck. Coats was bleeding from a cut in his mouth, was tested for a concussion and was listed as day to day.

Rays 7, Twins 4 — Evan Longoria homered for the third straight game, and Matt Andriese worked five innings in a rain-shortened start to pick up his fourth win as Tampa Bay won in Minneapolis.

Longoria’s fifth-inning home run was one of four for the Rays on the cloudy day, and the second of three allowed by Twins starter Ervin Santana (1-5). Steven Souza Jr.’s three-run shot off Santana in the fourth put the Rays ahead for good, and Logan Morrison’s two-run homer in the seventh against Michael Tonkin put the game out of reach to give Tampa Bay its second consecutive win.

Hank Conger — who came in hitting .188 with one homer — had a solo shot in the third.

Andriese (4-0) allowed three runs, one unearned, in five innings — his shortest start this season thanks in part to a 70-minute rain delay in the sixth.

Astros 6, Athletics 5 — Carlos Correa had three hits and his RBI single with one out in the 12th inning lifted host Houston.

After Jed Lowrie hit a tying home run with two outs in the ninth for Oakland, the Astros came back to win.

George Springer started Houston’s 12th with a double off Ryan Madson (2-2) and advanced to third on a sacrifice bunt by Jose Altuve. Correa then shot a single down the right field line to give Houston its seventh win in eight games.

Scott Feldman (3-3) plunked Khris Davis with two outs in the 12th before a single by Yonder Alonso. But Feldman retired Marcus Semien to end the inning.

Mets 6, Marlins 4 — Michael Conforto ended an 0-for-20 skid with an RBI single in the eighth and scored the tiebreaking run on pinch hitter Matt Reynolds’s two-out single to help New York rally in Miami.

Conforto also hit a sacrifice fly in the sixth. He batted .365 in April, but the recent slump has dropped his average to .247. The left fielder was a last-minute addition to the lineup when slugger Yoenis Cespedes was scratched because of a sore right hip, the latest in a wave of injuries for the Mets.

Reynolds put New York ahead in the eighth with a two-out single for his second hit and first RBI of his big league career. Alejandro De Aza contributed a two-out, two-run double in the ninth.

Brewers 6, Phillies 3 — Domingo Santana hit a tiebreaking solo homer in the eighth and Jonathan Villar went deep for the third straight game for visiting Milwaukee.

Pirates 8, Angels 7 — Gregory Polanco and Matt Joyce hit home runs during a five-run seventh inning, Jeff Locke got his career-best fourth straight win, and host Pittsburgh ended a four-game skid.

Polanco made it 4-3 by leading off the seventh with a 461-foot drive to right field, his ninth, off Fernando Salas (2-2). Joyce hit for Locke and capped the rally with a three-run shot to center field off Greg Mahle that made it 8-3.

Mark Melancon pitched a perfect ninth for his 17th save in 18 opportunities.

Jung Ho Kang hit a two-run shot and has eight homers in 23 games this season for Pittsburgh. Starling Marte and Josh Harrison each added three hits.

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Shortstop Corey Seager homered three times, driving in the go-ahead run with his second shot in the sixth inning, as Los Angeles beat host Atlanta, 4-2, on Friday night.

It was the second multi-homer game of Seager’s career, with the young shortstop blasting two against the Cardinals on May 15.

He became the first Dodgers rookie with three homers in a game since Don Demeter on April 21, 1959, against the Giants at the Los Angeles Coliseum.

Seager has been batting .317 with 6 doubles, 10 homers and 19 RBIs in his last 30 games since May 3. Seager has a team-leading 12 homers this season.