A grand jury Wednesday indicted a Newton man on motor vehicle homicide charges for allegedly slamming his SUV into a local restaurant in March, killing two people and injuring several others, prosecutors said.

Authorities say Bradford Casler, 55, was driving his Volkswagen Touareg SUV down Chestnut Street in Newton around 6:10 p.m. on March 1 when he crossed over Washington Street and struck multiple cars before plowing into the front of Sweet Tomatoes Pizza.

Two patrons, Eleanor Miele, 57, of Watertown, and Gregory D. Morin, 32, of Newton, were killed. Seven others were hurt.

Casler is charged with two counts of motor vehicle homicide and one count of operating a motor vehicle to endanger, Middlesex District Attorney Marian T. Ryan’s office said in a statement. His arraignment in Middlesex Superior Court has not been scheduled.

A spokeswoman for Ryan declined to say what evidence led investigators to charge Casler, a realtor with three previous accidents on his driving record. Casler’s driver’s license was revoked after the crash as an “immediate threat’’ to the public, prosecutors said.

Casler could not be reached for comment. His lawyer, David Meier, described the incident as a “horrible, horrible tragedy.’’

“Mr. Casler feels incredible sorrow for the victims and their families every single day,’’ he said. “Unfortunately, his health and physical condition could not have prevented such a tragic accident.’’

Meier declined to comment further.

Authorities have not said what might have caused Casler to lose control of his vehicle. One person who knows him well previously told the Globe that Casler suffers from multiple sclerosis. She said he walked with a stagger and had balance problems, speaking on condition of anonymity to protect her privacy.

Casler’s accidents occurred in Waltham in 1998, in Brookline in 2004, and in Needham in 2010, according to RMV records.

The Newton crash occurred during the dinner rush at the popular restaurant and sent passersby rushing to pull victims from the rubble. On 911 calls that poured in after the crash, screams could be heard in the background.

“A car just went full-speed into the restaurant,’’ one caller said. “I’m sure there are many people hurt. Whoever was in that restaurant and in that car.’’

Another frantic caller urged the dispatcher to hurry and send “the ambulance, everything’’ as fast as possible.

“Oh God, please!’’ she cried.

Relatives of Miele’s and Morin’s could not be reached for comment Wednesday.

Shortly after the crash, Miele’s husband, George Miele, told the Globe he had “lost my best friend.’’ Eleanor Miele was on her way to volunteer at church when she stopped for pizza at the restaurant, he said.

George Miele said his wife of 37 years had spent time before the crash gluing Easter baskets for needy children.

Morin, an associate at the law firm of Latham & Watkins in Boston, had a wife and young daughter. After his death, the firm remembered him as a “wonderful colleague and friend to many in Boston and throughout our firm.’’

Evan Allen, Kathy McCabe, and John R. Ellement of the Globe staff and Globe correspondents Samantha Gross and Ellen Ishkanian contributed to this report. Travis Andersen can be reached at travis.andersen@globe.com. Andy Rosen can be reached at andrew.rosen@globe.com.